PCI-32765 cas:936563-96-1

Ibrutinib (PCI-32765) is a potent and highly selective Brutons tyrosine kinase (Btk)inhibitor with IC50 of 0.5 nM in cell-free assays,modestly potent to Bmx, CSK,FGR,BRK,HCK,less potent to EGFR Yes,ErbB2,JAK3etc.Ibrutinib is applicable as a Btk ligand in the synthesis of a series of PROTACs including P13I.

msds---PCI-32765